ADVATE is a medicine used to replace clotting factor (factor VIII or antihemophilic factor) that is missing in people with hemophilia A (also called “classic” hemophilia). ADVATE is used to prevent and control bleeding in adults and children (0-16 years) with hemophilia A. Your healthcare provider (HCP) may give you ADVATE when you have surgery. ADVATE can reduce the number of bleeding episodes in adults and children (0-16 years) when used regularly (prophylaxis). ADVATE is not used to treat von Willebrand disease.

What are possible side effects of ADVATE?

Side effects that have been reported with ADVATE include: cough, headache, joint swelling/aching, sore throat, fever, itching, unusual taste, dizziness, hematoma, abdominal pain, hot flashes, swelling of legs, diarrhea, chills, runny nose/congestion, nausea/vomiting, sweating, and rash. Tell your HCP about any side effects that bother you or do not go away or if your bleeding does not stop after taking ADVATE.

ADVATE® [Antihemophilic Factor (Recombinant)] Patient Experience.

ADVATE Has Health-Related Quality-of-Life Results

After 12 months of prophylaxis treatment with ADVATE, people with hemophilia A rated improvements in select health-related quality-of-life measures compared with on-demand treatment.^1-3

Improvements observed in 2 areas:

Bodily pain

Reduced levels of pain and
improvements in the limitations of
work due to pain.^1,2

Role physical

Improvements in the ability to
perform work or other daily
activities.^1,2

Changes were not seen in:

Physical
functioning

Changes not observed in limitations
to a range of minor and major
physical activities.^1,2

General health

Changes not observed in the views
and expectations of overall
health.^1,2

Clinically meaningful changes were not seen in the mental health-related component score and subcategories of Mental Health, Role Emotional, Social Functioning, and Vitality.¹